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Background The purpose of this research is to determine the correlation between IGFBP-4/IGF-I expression and the clinical status of esophageal squamous cell carcinoma (ESCC). Materials and methods Immunohistochemical staining for IGFBP-4 and IGF-I was performed in 61 clinical samples. The correlation between IGFBP-4/IGF-I staining and clinicopathological features was examined statistically. In addition,...
A 64-year-old man underwent distal gastrectomy for gastric cancer. His postoperative recovery was uneventful until he suddenly started complaining of difficulty swallowing. Fluoroscopy revealed narrowing of the abdominal esophagus into a spindle-like shape. Endoscopic esophageal balloon dilatation was performed with no improvement in his condition. We concluded that the patient could not eat because...
Alport’s syndrome–diffuse leiomyomatosis (AS–DL) is a rare clinical entity. The syndrome consists of hematuric nephropathy, ocular lesions, and sensorineural deafness associated with leiomyomas of the gastrointestinal, respiratory and female reproductive tracts. Esophageal leiomyomatosis is characterized by diffuse proliferation of the esophageal wall smooth muscle layer, causing obstruction. The...
Esophageal schwannoma is extremely rare, and it is difficult to confirm a definitive diagnosis preoperatively. We report the case of a 67-year-old male with an asymptomatic esophageal schwannoma with a major axis of 6 cm. Computed tomographic angiography was very useful for determining a safe and efficient route of access to the tumor. Although high 18F-fluorodeoxyglucose uptake and high signal were...
Gastrointestinal stromal tumors (GISTs) of the esophagus are a rare entity. Diagnosis of GIST is currently based on immunohistochemical staining of c-KIT or CD34. However, some tumors have clinicopathologic features of GIST but do not express c-KIT or CD34. A few GISTs contain mutations within a receptor tyrosine kinase protein, platelet-derived growth factor receptor alpha (PDGFRA). We herein report...
Background Intra-thoracic stomach (ITS) is a rare type of hiatal hernia. Laparoscopic surgery for ITS is technically demanding due to the distorted surgical anatomy. We incorporated assistive esophagoscopy during laparoscopic surgery for ITS. In this study, we assessed the clinical value of esophagoscopy in laparoscopic surgery. Methods A retrospective data analysis of 11 consecutive patients with...
We herein report a rare case of adenocarcinoma arising in an interposed colon. A 71-year-old male underwent total thoracic esophagectomy for thoracic esophageal cancer followed by antesternal reconstruction using the right colon. Seven months later, 18F-fluorodeoxy-glucose positron emission tomography revealed increased uptake in the interposed colon. Endoscopy detected a mass 25 mm in diameter in...
Amelanotic primary malignant melanoma of the esophagus (PMME) is extremely rare. We report a case of amelanotic PMME that was accurately diagnosed and subsequently treated by radical resection with adjuvant chemotherapy. A 69-year-old woman was admitted to our hospital because of dysphagia. Endoscopic examination revealed a tumor without pigmentation in the upper thoracic esophagus, and melanosis...
We report a 78-year-old male who underwent successful resection of a gastric tube cancer by hand-assisted thoracoscopic surgery. The patient was initially placed in the supine position, and the abdominal portion of the gastric tube was mobilized via upper midline laparotomy. A pedicled colonic graft supplied by the left colic artery was prepared. The patient was then moved to the left decubitus position,...
Background Postoperative morbidity after esophagectomy for esophageal cancer is still frequent. Tools for prediction of postoperative complications have been sought, with the estimation of physiologic ability and surgical stress (E-PASS) scoring system being one of the candidates. The aim of this study was to determine the usefulness of the E-PASS system for risk assessment of esophagectomy. Methods...
Background Neoadjuvant or induction chemotherapy with docetaxel, cisplatin, and 5-fluorouracil (DCF) is regarded as one of the most promising regimens for locally advanced esophageal squamous cell carcinoma (ESCC), but has a high incidence of adverse events. We retrospectively evaluated adverse events in patients with ESCC who received DCF. Methods Between December 2009 and May 2012, 57 patients...
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